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Significant events in Genomics


1865

Gregory Mendel publishes evidence for the discreteness and combinatorial rules of inherited traits.[1]

1879

Fleming visualized chromosomes and was the first to detail how chromosome behave during animal cell division (mitosis).[2]

1900

Carl Correns, Hugo de Vries & Erich von Tschermak discover Mendel's principles: this important event marks the beginning of modern genetics.[3]

1910

Thomas Hunt Morgan shows that genes reside on chromosomes.[4]

1953

Watson and Crick determine that deoxyribonucleic acid (DNA) is a double-strand helix of nucleotides.[5]

1970

Restriction enzymes were discovered in studies of a bacterium, Haemophilus influenzae, enabling scientists to cut and paste DNA.[6]

1983

Kary Banks Mullis invents the polymerase chain reaction enabling the easy amplification of DNA.[7]

1995

The genome of bacterium Haemophilus influenzae is the first genome of a free living organism to be sequenced.[8]

1996

Saccharomyces cerevisiae, a yeast species, is the first eukaryote genome sequence to be released.[9]

1998

Caenorhabditis elegans becomes the first animal whose genome is totally sequenced.[10]

2003

Successful completion of Human Genome Project with 99% of the genome sequenced to a 99.99% accuracy.[11]


  1. Mendel, G., 1866, Versuche über Pflanzen-Hybriden. Verh. Naturforsch. Ver. Brünn 4: 3–47 (in English in 1901, J. R. Hortic. Soc. 26: 1–32)
  2. National Human Genome Research Institute (NIH), Dynamic timeline, www.genome.gov
  3. Roberts, H. F. Plant Hybridization before Mendel. Princeton: Princeton University Press, 1929.
  4. Miko, I. (2008) Thomas Hunt Morgan and sex linkage. Nature Education 1(1):143
  5. Watson, JD, Crick, FH (Apr 1953). "Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid". Nature 171 (4356): 737–8.
  6. Pray, L. (2008) Restriction enzymes. Nature Education 1(1):38
  7. Ma Hongbao The Journal of American Science, 1(3), 2005, Development Application of Polymerase Chain Reaction (PCR)
  8. Fleischmann RD, Adams MD, White O, et al. (July 1995). "Whole-genome random sequencing and assembly of Haemophilus influenzae Rd". Science 269 (5223): 496–512
  9. Goffeau, A.; Barrell, B. G.; Bussey, H.; Davis, R. W.; Dujon, B.; Feldmann, H.; Galibert, F.; Hoheisel, J. D.; Jacq, C.; Johnston, M.; Louis, E. J.; Mewes, H. W.; Murakami, Y.; Philippsen, P.; Tettelin, H.; Oliver, S. G. (1996). "Life with 6000 Genes". Science 274(5287): 546, 563–7.
  10. Consortium, T. C. e. S. 1998. Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 282:2012-8.
  11. National Human Genome Research Institute (NIH), News Release 2003, www.genome.gov

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Lab Reporter - A publication of Fisher Scientific


LIFE SCIENCE

Venom Immunotherapy

Until recently, the concept of venom immunotherapy was primarily associated with stinging insects, but recent developments are redefining this field of study.

Read More

LIFE SCIENCE

Cell Transformation and the Fight Against Fat

Researchers from McGill University in Montreal have discovered a means of stimulating the body to burn fat rather than store it, which could aid in the evergrowing battle against obesity, diabetes and cardiovascular diseases.

Read More


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