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ZBTB33 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 55270-1-AP-20UL
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Description
ZAP70, a 70 kDa member of the Syk tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Upon T cell antigen receptor (TCR) engagement, ZAP70 is phosphorylated on tyrosines 292, 315 and 319 in the interdomain B, located between the SH2 and kinase domains. Phosphorylation of both tyrosines 315 (a Vav binding site) and 319 (a Lck binding site) enhances ZAP70 function in mediating lymphocyte signaling, while tyrosine 292 terminates the transient activation of ZAP70 and attentuates lymphocyte signaling.Specifications
| ZBTB33 | |
| Polyclonal | |
| Unconjugated | |
| ZBTB33 | |
| KAISO, ZBTB33, ZNF kaiso, ZNF348 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 10009 | |
| -20°C | |
| Liquid |
| Western Blot, Immunoprecipitation | |
| 0.43 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q86T24 | |
| ZBTB33 | |
| Peptide | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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