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ZBED1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 26140-1-AP-20UL
This item is not returnable.
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Description
ZBED1, also known as DREF, is the human homolog of the Drosophila protein DREF, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation. RNA interference (RNAi) experiments targeting ZBED1 RNA resulted in the inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, suggesting that ZBED1 also plays a role in cell proliferation in human cells. At least 22 ribosomal proteins (RPs) possess ZBED1 binding sites in their promoters; anti-ZBED1 RNAi also resulted in decreased RP gene expression. Immunoprecipitation analyses have shown that ZBED1 self-associates in vivo via a carboxyl-terminal hATC domain, and this self-association is required for nuclear localization and DNA binding.Specifications
| ZBED1 | |
| Polyclonal | |
| Unconjugated | |
| ZBED1 | |
| ALTE, DREF, dREF homolog, hDREF, KIAA0785, TRAMP, ZBED1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 9189 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 0.27 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O96006 | |
| ZBED1 | |
| ZBED1 Fusion Protein Ag23578 | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG |
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