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YTHDF2 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1696.32 NOK - 4796.50 NOK

Specifications

Antigen YTHDF2
Concentration 0.25 mg/mL
Applications Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation, Immunofluorescence, Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16843235
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Proteintech
24744-1-AP-20UL
20 μL
1696.32 NOK
20µL
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16833235
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Proteintech
24744-1-AP-150UL
150 μL
4796.50 NOK
150µL
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Description

Description

Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates mRNA stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability. Acts as a regulator of mRNA stability: binding to m6A-containing mRNAs results in the localization to mRNA decay sites, such as processing bodies (P-bodies), leading to mRNA degradation. Also acts as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5′-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation.
Specifications

Specifications

YTHDF2
Immunohistochemistry (Paraffin), Immunocytochemistry, Immunoprecipitation, Immunofluorescence, Western Blot
Unconjugated
Rabbit
Human
Q9Y5A9
51441
YTHDF2 Fusion Protein Ag5922
Primary
-20°C
YTHDF2
0.25 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
CLL associated antigen KW 14, HGRG8, NY REN 2, YTH domain family protein 2, YTH domain family, member 2, YTHDF2
YTHDF2
IgG
Antigen Affinity Chromatography
Antibody
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Documents

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