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TWIST1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 25465-1-AP-20UL

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Product Code. 16844045

  • 1696.32 NOK / 20µL

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Description

Description

The antibody reacts specifically with TWIST1 protein.

TWIST1 acts as a transcriptional regulator. It inhibits myogensis by sequestering E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. TWIST1 also represses proinflammatory cytokines such as TNFA and IL1B. TWIST also regulates cranial suture patterning and fusion and gene expression differentially depending on dimer composition. Mutations in the gene are implicated in Saethre-Chotzen syndrome, a disease characterized by coronal synostosis, brachycephaly, low front hairline, facial asymmetry, hypertelorism, broad halluces, and clinodactyly.
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TWIST1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech > 20 μL; Unconjugated

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