missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Analysis Products
  4. Cell Based Assays
  5. Signal Transduction Reagents and Kits
  6. 15404559

Thermo Scientific Chemicals Sulindac Sulfide

CAS: 32004-67-4 | C20H17FO2S, C20H17FO2S | 340.41 g/mol

Brand:  Thermo Scientific Chemicals J62104.MC


Quantity 100 mg

Product Code. 15404559

  • 4800.00 NOK / 100mg

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Description

It is also shown to inhibit growth and induce apoptosis in human prostate cancer cells through a COX-1 and COX-2 independent mechanism. Sulindac sulfide is an analgesic that has antiproliferative and apoptotic effects. It inhibits the expression and activity of cyclooxygenase-2 in human colon cancer cells, and reduces tumor burden in adenomatous polyposis patients. Human endothelial cells, HMEC-1 were treated with Sulindac sulfide and the effect on cell survival was studies by MTT assay.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

100 mg
Active metabolite of sulindac; inhibits cyclooxygenase-1
C20H17FO2S, C20H17FO2S
189°C to 191°C
Signal Transduction Reagent
MFCD00869764
CSC1=CC=C(\C=C2/C(C)=C(CC(O)=O)C3=CC(F)=CC=C23)C=C1
340.41
Yellow
32004-67-4
340.41g/mol
Soluble in DMSO
Powder
LFWHFZJPXXOYNR-RQZCQDPDSA-N
2-[(1E)-5-fluoro-2-methyl-1-{[4-(methylsulfanyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid
Product Suggestions

Product Suggestions

Videos
Safety and Handling

Safety and Handling

Product Identifier
  • Sulindac sulfide

Signal Word
  • Danger

Hazard Category
  • Acute toxicity Category 3
  • Reproductive toxicity on or via lactation
  • Reproductive toxicity Category 2
  • Respiratory sensitiser Category 1
  • Skin sensitiser Category 1
  • Specific target organ toxicity after repeated exposure Category 2

Hazard Statement
  • H301-Toxic if swallowed.
  • H317-May cause an allergic skin reaction.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H361-Suspected of damaging fertility or the unborn child.
  • H362-May cause harm to breast-fed children.
  • H373-May cause damage to organs.

Precautionary Statement
  • P201-Obtain special instructions before use.
  • P263-Avoid contact during pregnancy/while nursing.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P284-¢In case of inadequate ventilation! wear respiratory protection.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
  • P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .

Supplemental information
  • MIXTURE LIST-Contains : Sulindac sulfide

SDS Documents

Documents

Certificates
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.