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  6. Staurosporine, 99+%, Thermo Scientific Chemicals

Staurosporine, 99+%, Thermo Scientific Chemicals

Staurosporine (staurosporin, CAS # 62996-74-1) is a bacterial alkyloid isolated from Streptomyces staurosporeus.

1795.00 NOK - 11185.00 NOK

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Chemical Identifiers

CAS 62996-74-1
Molecular Formula C28H26N4O3
Molecular Weight (g/mol) 466.541
MDL Number MFCD00077402
InChI Key HKSZLNNOFSGOKW-ZYSRIHRCSA-N
Synonym Antibiotic AM-2282
PubChem CID 49831000
SMILES CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
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15495139
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Thermo Scientific Alfa Aesar
J62837.M^ 		1 mg
1795.00 NOK
1mg
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Thermo Scientific Alfa Aesar
J62837.#0 		5 mg
6125.00 NOK
5mg
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Thermo Scientific Alfa Aesar
J62837.MA 		10 mg
11185.00 NOK
10mg
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Description

Description

Broad spectrum protein kinase inhibitor Staurosporine is used as anti-fungal and anti-hypertensive, which results to study the anti-cancer treatment. It acts as a precursor to protein kinase inhibitor midostaurin. It is also used to induce cell death in Swiss Webster primary macrophage cells and to study the effect of caspase activation on human sperm quality.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Staurosporine is an indolocarbazole alkaloid capable of permeating cell membranes
  • Staurosporine has anti-cancer properties that can induce apoptosis
  • Staurosporine is a broad inhibitor of protein kinases, preventing growth and division cycles

Application

  • Staurosporine is used for research on acute myeloid leukemia
  • It is suitable for research applications including cell culture and biochemistry
Specifications

Chemical Identifiers

62996-74-1
466.541
HKSZLNNOFSGOKW-ZYSRIHRCSA-N
49831000
C28H26N4O3
MFCD00077402
Antibiotic AM-2282
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

Specifications

Staurosporine
62996-74-1
Yellow
MFCD00077402
14,8802
Soluble in DMSO or ethanol;Soluble in dimethyl sulfoxide ,dimethyl formamide,ethyl acetate,hot acetone and ethanol; Slightly soluble in chloroform and methanol; Insoluble in water.
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
49831000
≥99%
Powder
240°C to 243°C
C28H26N4O3
1060573
Antibiotic AM-2282
HKSZLNNOFSGOKW-ZYSRIHRCSA-N
466.541
466.54
Staurosporine
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Safety and Handling

Safety and Handling

GHS H Statement
H350
May cause cancer.

P201-P202-P280-P308+P313-P501c

H351

missing translation for 'rtecsNumber' : KD5084000

missing translation for 'tsca' : No

missing translation for 'storageNote' : -30° to -10°C

Recommended Storage : Store at -20°C

Product Identifier
  • Staurosporine

Signal Word
  • Warning

Hazard Category
  • Carcinogenicity Category 2

Hazard Statement
  • H351-Suspected of causing cancer.

Precautionary Statement
  • P201-Obtain special instructions before use.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only

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