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SIRT6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 13572-1-AP-150UL
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Description
This antibody is a rabbit polyclonal antibody raised against full length human SIRT6 antigen.
The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT6 is a histone H3 lysine 9 deacetylase and is thought to stabilize the DNA-dependent protein kinase at double-stranded DNA breaks and may have a role in the process of mammalian aging.Specifications
| SIRT6 | |
| Polyclonal | |
| Unconjugated | |
| SIRT6 | |
| SIR2 like protein 6, SIR2L6, SIRT6 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 299638, 50721, 51548 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.29 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P59941, Q8N6T7 | |
| SIRT6 | |
| SIRT6 Fusion Protein Ag4469 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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