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Poly-D-Lysine Hydrobromide, MP Biomedicals™
Enhances cell adhesion to solid substrates. Poly-D-Lysine Hydrobromide, MP Biomedicals is a synthetic amino acid that binds to DNA, red cell membrane and any negatively charged protein. It has been shown to eliminate prion proteins from infected cells. Mo
Brand: MP Biomedicals 0215017580
Quantity | 100 mg |
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Description
When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. It is a compromise between easier-to-use lower molecular weight products and the extremely viscous higher molecular weights.
Poly-lysine enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Both the D- and L- forms can be used as a coating substrate, since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest it. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.
Poly-D-Lysine Hydrobromide is typically used as a coating substrate for culture dishes, slides, etc. Other uses for poly-lysine have been reported as well:
- Conjugation to methotrexate for increased drug transport
- Microencapsulation of islets
- Use in simple reproducible procedure for chromosomal preparations from a variety of tissues
- Immobilation of living cells in biocompatible semipermeable microcapsules
- In the preparation of polycationic beads
- Conjugation to albumin and horseradish peroxidase to enhance cellular uptake

Specifications
27964-99-4 | |
d-lysine hydrobromide | |
MEXAGTSTSPYCEP-NUBCRITNSA-N | |
(2R)-2,6-diaminohexanoic acid;hydrobromide | |
100 mg | |
70000-150000 |
C6H15BrN2O2 | |
50mg/mL, H2O | |
C(CCN)CC(C(=O)O)N.Br | |
227.102 | |
87493163 | |
Powder |
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