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Poly-D-Lysine Hydrobromide, MP Biomedicals™

Enhances cell adhesion to solid substrates. Poly-D-Lysine Hydrobromide, MP Biomedicals is a synthetic amino acid that binds to DNA, red cell membrane and any negatively charged protein. It has been shown to eliminate prion proteins from infected cells. Mo

Brand:  MP Biomedicals 0215017580

Quantity 100 mg

Product Code. 11466632

  • 3950.00 SEK / 100mg

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Description

Description

When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. It is a compromise between easier-to-use lower molecular weight products and the extremely viscous higher molecular weights.

Poly-lysine enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Both the D- and L- forms can be used as a coating substrate, since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest it. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.

Poly-D-Lysine Hydrobromide is typically used as a coating substrate for culture dishes, slides, etc. Other uses for poly-lysine have been reported as well:

  • Conjugation to methotrexate for increased drug transport
  • Microencapsulation of islets
  • Use in simple reproducible procedure for chromosomal preparations from a variety of tissues
  • Immobilation of living cells in biocompatible semipermeable microcapsules
  • In the preparation of polycationic beads
  • Conjugation to albumin and horseradish peroxidase to enhance cellular uptake
TRUSTED_SUSTAINABILITY
Specifications

Specifications

27964-99-4
d-lysine hydrobromide
MEXAGTSTSPYCEP-NUBCRITNSA-N
(2R)-2,6-diaminohexanoic acid;hydrobromide
100 mg
70000-150000
C6H15BrN2O2
50mg/mL, H2O
C(CCN)CC(C(=O)O)N.Br
227.102
87493163
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