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PERK/EIF2AK3 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 20582-1-AP-20UL
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Description
The antibody is specific to PERK.
Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function.Specifications
| PERK/EIF2AK3 | |
| Polyclonal | |
| Unconjugated | |
| EIF2AK3 | |
| EIF2AK3, HRI, HsPEK, Pancreatic eIF2 alpha kinase, PEK, PERK, WRS | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 13666, 9451 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot, Immunocytochemistry | |
| 0.46 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q9NZJ5, Q9Z2B5 | |
| EIF2AK3 | |
| Peptide | |
| 20 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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