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PARL Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1696.32 NOK - 4796.50 NOK

Specifications

Antigen PARL
Concentration 0.47 mg/mL
Applications Western Blot, Immunohistochemistry (Paraffin)
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16865075
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Proteintech
26679-1-AP-20UL
20 μL
1696.32 NOK
20µL
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16855075
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Proteintech
26679-1-AP-150UL
150 μL
4796.50 NOK
150µL
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Description

Description

PARL is a mitochondrial integral membrane protein and a member of the highly conserved rhomboid superfamily of membrane proteins. PARL is required for the control of apoptosis during postnatal growth and is required for the processing of OPA1, a protein that prevents the release of cytochrome C from the mitochondria in response to apoptotic signals. In lymphocytes and neurons, PARL′s association with other proteins, such as the Bcl-2 family-related protein Hax1 and Omi can lead to the proteolytic processing of Omi by PARL, preventing the accumulation of Bax, thereby suppressing apoptosis. Variations in this gene have been associated with increased risk for type 2 diabetes. PARL may also play a role in the progression of Alzheimer′s disease through its associations with presenilin-1 and -2. Multiple isoforms of PARL are known to exist.
Specifications

Specifications

PARL
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Human
Q9H300
55486
PARL Fusion Protein Ag24789
Primary
-20°C
PARL
0.47 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
PARL, Pbeta, PRO2207, PSARL, PSARL1, PSENIP2, RHBDS1
PARL
IgG
Antigen Affinity Chromatography
Antibody
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SDS
Documents

Documents

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