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NFKB1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 23576-1-AP-20UL
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Beschreibung
This antibody can bind p105 isoforms of NFKB1.
NF-kB is a nuclear transcription factor activated by various extra and intracellular stimuli such as cytokines, UV radiation, stress, in injury, and by bacterial and viral products. It is involved in regulation of various cellular events including cell growth, differentiation, proliferation, apoptosis and inflammation. NFKB1 (p50), a 50 kDa functional sub-unit of NF-kB, is a member of Rel protein family. It is synthesized as a p105 precursor protein and consists of an N-terminal conserved RHD-region containing nuclear localization signal, DNA-binding and dimerization domains. NFKB1 (p50) forms homodimers or heterodimerizes with p65, forming the functional NF-kB factor. NFKB1 (p50) directs the nuclear translocation of NF-kB and is instrumental in its DNA-binding. Pathological role of NF-kB has been suggested in AIDS, hematogenic cancer cell metastasis and rheumatoid arthritis.Spezifikation
| NFKB1 | |
| Polyclonal | |
| Unconjugated | |
| NFKB1 | |
| DNA binding factor KBF1, EBP 1, KBF1, NF kappa B, NFKB p105, NFKB p50, NFKB1, NFKB1,p105, NFKB1,p105,p50, nfkb1a, p105, p50 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 4790 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot, Immunofluorescence | |
| 0.54 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P19838 | |
| NFKB1 | |
| NFKB1 Fusion Protein Ag20297 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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