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Thermo Scientific Chemicals Mitomycin C, contains 2 mg Mitomycin C and 48 mg NaCl

Product Code. 10286710 Shop All Thermo Scientific Chemicals Products
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Quantity:
2 mg
Unit Size:
2mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Mitomycin C, CAS # 50-07-7, is a methylazirinopyrroloindoledione complex isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. It is a versatile and potent compound with antibiotic activity and may have potential therapeutic value in the treatment of cancer. | CAS: 50-07-7 | C15H18N4O5 | 334.32 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

  • Mitomycin C is a water soluble, blue-violet crystalline powder, unstable in light and acidic conditions, but may be stably stored at 2-8°c
  • Bio-reduced mitomycin C generates oxygen radicals, alkylates DNA, and produces inter-strand DNA cross-links, thereby inhibiting DNA synthesis

Applications

  • Mitomycin C is preferentially toxic to hypoxic cells that are resistant to cancer therapy, and is therefore used to study its potential therapeutic effect on advanced stages of cancer
  • At high concentrations, mitomycin C inhibits RNA and protein synthesis and demonstrates strong antibiotic properties towards both Gram-positive and Gram-negative bacteria
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material Mitomycin C
CAS 50-07-7, 7647-14-5
Melting Point >360.0°C
Color Blue-Violet
Packaging Ampoule
Molecular Formula C15H18N4O5
MDL Number MFCD00078109
Quantity 2 mg
Merck Index 15, 6300
Synonym mitomycin c, mitomycin, ametycine, mutamycin, ametycin, mitocin-c, mitomycinum, mytomycin, mytozytrex, mitomycin-c
Solubility Information Solubility in water: soluble. Other solubilities: soluble in methanol, acetone, butyl acetate and, cyclohexanone;, slightly soluble in benzene, ccl4, diethyl ether;, practically insoluble in petroleum ether.
InChI Key NWIBSHFKIJFRCO-WUDYKRTCSA-N
SMILES CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N
Molecular Weight (g/mol) 334.32
PubChem CID 5746
ChEBI CHEBI:27504
Formula Weight 334.32
Percent Purity ≥99% with regard to the non-formulated material
Physical Form Powder
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Safety and Handling

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Product Identifier
  • Mitomycin C
 Signal Word
  • Warning
 Hazard Category
  • Acute toxicity Category 4
  • Carcinogenicity Category 2
 Hazard Statement
  • H351-Suspected of causing cancer.
  • H302-Harmful if swallowed.
 Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P312-IF SWALLOWED: Call a POISON CENTER or doctor/physician/ if you feel unwell.
SDS

RUO – Research Use Only

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