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  7. Hypoxanthine, 99%, Thermo Scientific Chemicals

Hypoxanthine, 99%, Thermo Scientific Chemicals

Product Code. 11480373
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Quantity:
5 g
25 g
100 g
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol A (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol å (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.

Solubility
It does not mix appreciably with water (1:1400). Small octahedra crystals from water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong oxidizing agents. Stable under recommended storage conditions. Sterilize by filtration through a 0.22 µm filter.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 68-94-0
Molecular Formula C5H4N4O
Molecular Weight (g/mol) 136.11
MDL Number MFCD00005725
InChI Key FDGQSTZJBFJUBT-UHFFFAOYSA-N
Synonym hypoxanthine, 6-hydroxypurine, 9h-purin-6-ol, sarkin, 6-oxopurine, sarcine, sarkine, 3h-purin-6-ol, 7h-purin-6-ol, purin-6 1h-one
PubChem CID 790
ChEBI CHEBI:17368
IUPAC Name 3,7-dihydropurin-6-one
SMILES O=C1N=CNC2=C1NC=N2

Specifications

Melting Point >300°C
Quantity 100 g
Beilstein 5811
Merck Index 14,4869
Solubility Information It does not mix appreciably with water (1:1400). Small octahedra crystals from water.
Formula Weight 136.11
Percent Purity 99%
Chemical Name or Material Hypoxanthine

RUO – Research Use Only

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