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Hydroxyurea, 98%, Thermo Scientific Chemicals
CAS: 127-07-1 | CH4N2O2 | 76.055 g/mol
429.00 NOK - 4495.00 NOK
Chemical Identifiers
CAS | 127-07-1 |
---|---|
Molecular Formula | CH4N2O2 |
Molecular Weight (g/mol) | 76.055 |
MDL Number | MFCD00007943 |
InChI Key | VSNHCAURESNICA-UHFFFAOYSA-N |
Synonym | hydroxycarbamide, n-hydroxyurea, hydrea, 1-hydroxyurea, oxyurea, carbamoyl oxime, biosupressin, hydroxycarbamine, onco-carbide, carbamohydroxamic acid |
PubChem CID | 3657 |
ChEBI | CHEBI:44423 |
IUPAC Name | hydroxyurea |
SMILES | C(=O)(N)NO |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
11469782
|
Thermo Scientific Alfa Aesar
A10831.03 |
1 g |
429.00 NOK
1g |
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11479782
|
Thermo Scientific Alfa Aesar
A10831.06 |
5 g |
1255.00 NOK
5g |
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11489782
|
Thermo Scientific Alfa Aesar
A10831.14 |
25 g |
4495.00 NOK
25g |
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Description
Hydroxyurea is used as an inhibitor of DNA synthesis and an anti-cancer drug. It is used as a precursor to prepare 1-hydroxy-5,6-dimethyl-1H-pyrimidine-2,4-dione via reaction with 2-methyl-3-oxo-butyric acid ethyl ester. It is used in the treatment of melanoma, resistant chronic myelocytic leukemia and recurrent metastatic or inoperable ovarian. It is also involved in reducing the rate of painful attacks in sickle-cell disease and has anti-retroviral properties in diseases such as AIDS.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
SolubilitySoluble in water, hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene.
Notes
Moisture sensitive. Store in cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
Chemical Identifiers
127-07-1 | |
76.055 | |
VSNHCAURESNICA-UHFFFAOYSA-N | |
3657 | |
hydroxyurea |
CH4N2O2 | |
MFCD00007943 | |
hydroxycarbamide, n-hydroxyurea, hydrea, 1-hydroxyurea, oxyurea, carbamoyl oxime, biosupressin, hydroxycarbamine, onco-carbide, carbamohydroxamic acid | |
CHEBI:44423 | |
C(=O)(N)NO |
Specifications
127-07-1 | |
98% | |
MFCD00007943 | |
hydroxycarbamide, n-hydroxyurea, hydrea, 1-hydroxyurea, oxyurea, carbamoyl oxime, biosupressin, hydroxycarbamine, onco-carbide, carbamohydroxamic acid | |
VSNHCAURESNICA-UHFFFAOYSA-N | |
hydroxyurea | |
3657 | |
76.06 |
∽140°C (decomposition) | |
CH4N2O2 | |
1741548 | |
Soluble in water,hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene. | |
C(=O)(N)NO | |
76.055 | |
CHEBI:44423 | |
Hydroxyurea |
Safety and Handling
P201-P202-P281-P308+P313-P501c
H340-H360D
missing translation for 'einecsNumber' : 204-821-7
missing translation for 'rtecsNumber' : YT4900000
missing translation for 'tsca' : No
Recommended Storage : Ambient temperatures
- Hydroxyurea
Signal Word
- Danger
Hazard Category
- Germ cell mutagenicity Category 1B
- Reproductive toxicity Category 1A
Hazard Statement
- H340-May cause genetic defects.
- H360D-May damage the unborn child.
Precautionary Statement
- P201-Obtain special instructions before use.
- P308+P313-IF exposed or concerned: Get medical advice/attention.
Supplemental information
- MIXTURE LIST-Contains : Hydroxyurea
RUO – Research Use Only
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