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HRD1/SYVN1 Mouse anti-Human, CoraLite 594, Clone: 2C8A7, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech CL594-67488-100UL

Product Code. 17224836

  • 5264.45 NOK / 100µL

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Description

Description

HRD1is also named as SYVN1(Synovial apoptosis inhibitor 1) , KIAA1810. It acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Two distinct binding sites mediate Hrd1 dimerization or oligomerization, one located within the transmembrane region and another within the cytosolic domain. (PMID:19864457).Western blot analysis detected abundant HRD1 expression in liver and kidney. Mouse liver and spleen expressed Hrd1 as an 85-kD protein(PMID:12646171).

Specifications

Specifications

HRD1/SYVN1
Monoclonal
1000 μg/mL
Mouse
Primary
Human
IgG2b
Immunofluorescence
2C8A7
CoraLite 594
100 μL
84447
Liquid
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