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G418 disulfate, Cell Culture Reagent
G418 sulfate, geneticin, CAS # 108321-42-2, is an antibiotic closely related to Gentamicin B, the common aminoglycoside antibiotic. | CAS: 108321-42-2 | C20H44N4O18S2 | 692.70 g/mol
Brand: Thermo Scientific Alfa Aesar J62671.06
6367.50 NOK valid until 2025-06-30
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| Quantity | 5 g |
|---|
This item is not returnable.
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Description
G418 disulfate is an aminoglycoside that is toxic to bacteria, yeast, protozoans and helminths. It prevents protein synthesis by blocking the elongation step in prokaryotic and eukaryotic ribosomes. It is used as a selection agent for G418 resistant bacteria or fungi after transformation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General description
• G418 sulfate (geneticin) is an aminoglycoside antibiotic isolated from Micromonospora rhodorangea
• G418 is a bacteriostatic that prevents polypeptide formation by inhibiting the elongation step of polypeptide synthesis
Applications
• G418 sulfate can be used for selection of genetically engineered cells in both eukaryotes and prokaryotes
• Laboratory grade for applications such as biochemistry
Chemical Identifiers
| 108321-42-2 | |
| 692.70 | |
| UHEPSJJJMTWUCP-KETIWVBHNA-N | |
| 134129582 |
| C20H44N4O18S2 | |
| MFCD00058314 | |
| Geneticin disulfate | |
| OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](C(C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)OC[C@]1(C)O |
Specifications
| G418 Disulfate | |
| 108321-42-2 | |
| 5 g | |
| MFCD00058314 | |
| Soluble in water. | |
| OS(O)(=O)=O.OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](C(C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)OC[C@]1(C)O | |
| 692.70 | |
| 692.71 | |
| G418 disulfate |
| Powder | |
| White | |
| C20H44N4O18S2 | |
| Geneticin disulfate | |
| UHEPSJJJMTWUCP-KETIWVBHNA-N | |
| (2R,3R,4R,5R)-2-[(1S,2R,3R,4S,6R)-4,6-diamino-3-[(2S,3S,4R,5S,6R)-3-amino-4,5-dihydroxy-6-[(1R)-1-hydroxyethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid | |
| 134129582 | |
| Cell Culture |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- G418 disulfate, Cell Culture Reagent
Signal Word
- Danger
Hazard Category
- Respiratory sensitiser Category 1
- Skin sensitiser Category 1
Hazard Statement
- H317-May cause an allergic skin reaction.
- H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Precautionary Statement
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P284-¢In case of inadequate ventilation! wear respiratory protection.
- P302+P352-IF ON SKIN: Wash with plenty of water/soap.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P333+P313-If skin irritation or rash occurs: Get medical advice/attention.
- P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .
Supplemental information
- MIXTURE LIST-Contains : G418 disulfate
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