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FADD Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

1696.32 NOK - 4796.50 NOK

Specifications

Antigen FADD
Concentration 0.13 mg/mL
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16803814
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Proteintech
14906-1-AP-20UL
20 μL
1696.32 NOK
20µL
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16893804
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Proteintech
14906-1-AP-150UL
150 μL
4796.50 NOK
150µL
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Description

Description

The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Specifications

Specifications

FADD
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry, Immunofluorescence
Unconjugated
Rabbit
Human, Mouse, Rat
Q13158, Q61160
14082, 266610, 8772
FADD Fusion Protein Ag6701
Primary
-20°C
FADD
0.13 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
FADD, GIG3, MORT1, Protein FADD
FADD
IgG
Antigen Affinity Chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications
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