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EIF3D Rabbit anti-Human, Mouse, Yeast, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 10219-1-AP-20UL

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Product Code. 16856463

  • 1696.32 NOK / 20µL

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Description

Description

eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.
Specifications

Specifications

EIF3D
Polyclonal
Unconjugated
EIF3D
eIF 3 zeta, eIF3 p66, eIF3 zeta, EIF3D, EIF3S7
Rabbit
Antigen Affinity Chromatography
RUO
55944, 8664
-20°C
Liquid
Western Blot, Immunofluorescence, Immunocytochemistry, Immunoprecipitation, Immunohistochemistry (Paraffin)
0.29 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O15371, O70194
Eif3d
EIF3D Fusion Protein Ag0268
20 μL
Primary
Mouse, Yeast, Human
Antibody
IgG
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