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  6. Dexamethasone, 96%, Thermo Scientific Chemicals

Dexamethasone, 96%, Thermo Scientific Chemicals

Dexamethasone, CAS# 50-02-2, is a synthetic adrenal corticosteroid that shows potent anti-inflammatory activity.

763.05 NOK - 3821.11 NOK

Chemical Identifiers

CAS 50-02-2
Molecular Formula C22H29FO5
Molecular Weight (g/mol) 392.47
MDL Number MFCD00064136
InChI Key UREBDLICKHMUKA-CXSFZGCWSA-N
Synonym dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
PubChem CID 5743
ChEBI CHEBI:41879
SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
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Product Code Brand Quantity Packaging Price Quantity & Availability  
Product Code Brand Quantity Packaging Price Quantity & Availability  
10053130
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Thermo Scientific Acros
230302500 		250 mg Glass bottle
763.05 NOK
250mg
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10502631
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Thermo Scientific Acros
230300010 		1 g Glass bottle
1622.50 NOK
1g
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10434225
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Thermo Scientific Acros
230300050 		5 g Glass bottle
3821.11 NOK
5g
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Description

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• Dexamethasone is a synthetic adrenal glucocorticoid that modulates carbohydrate metabolism, inhibits adrenocorticotropic hormone secretion, and has pronounced anti-inflammatory activity
• Dexamethasone can bind to specific nuclear steroid receptors, inhibiting pro-inflammatory signals, promoting anti-inflammatory signals, and interfering with NF-kB activation and apoptotic pathways

Applications

• It can be used to study apoptosis, cell signaling pathways, and gene expression
• This compound also shows adrenergic, antiemetic, and antineoplastic activities
• It has been used as an important regulator of cellular proliferation and differentiation in vitro human cell cultures
• Dexamethasone has been applied in culture media to promote the differentiation of adipose-derived stem cells into osteogenic tissue
• It is used in in vitro stimulation of primary normal human bronchial epithelial cells (NHBE) and airway smooth muscle (ASM)
• This compound is used for its ability to regulate T cell survival, growth, and differentiation.
• It can also inhibit the induction of nitric oxide synthase.

Specifications

Chemical Identifiers

50-02-2
392.47
UREBDLICKHMUKA-CXSFZGCWSA-N
5743
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
C22H29FO5
MFCD00064136
dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
CHEBI:41879

Specifications

50-02-2
White
Authentic
C22H29FO5
15, 2945
dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
95% min. (on dried substance)
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
392.47
CHEBI:41879
96%
Crystalline Powder
255.0°C to 261.0°C
0.5% max. (105°C, 3 hrs)
96%
MFCD00064136
+ 75.00
Solubility in water: 10mg/100mL (25 c). Other solubilities: soluble in acetone,ethanol and chloroform
UREBDLICKHMUKA-CXSFZGCWSA-N
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
5743
392.46
(HPLC) Passes test
Dexamethasone
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Safety and Handling

Safety and Handling

GHS H Statement:
Suspected of causing cancer.

GHS P Statement:
Use personal protective equipment as required.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

GHS Signal Word: Warning

missing translation for 'einecsNumber' : 200-003-9

Product Identifier
  • Dexamethasone

Signal Word
  • Warning

Hazard Category
  • Carcinogenicity Category 2

Hazard Statement
  • H351-Suspected of causing cancer.

Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.

SDS
Documents

Documents

Product Certifications

RUO – Research Use Only

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