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  6. Thermo Scientific Chemicals Cloxacillin sodium salt monohydrate

Thermo Scientific Chemicals Cloxacillin sodium salt monohydrate

Cloxacillin sodium salt monohydrate, CAS # 7081-44-9, is a compound that targets gram-positive bacteria and shows antibacterial activity.

707.79 NOK - 1926.00 NOK

Chemical Identifiers

CAS 7081-44-9
Molecular Formula C19H19ClN3NaO6S
Molecular Weight (g/mol) 475.876
InChI Key KCUWTKOTPIUBRI-VICXVTCVSA-M
PubChem CID 23675743
ChEBI CHEBI:34978
IUPAC Name sodium;(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrate
SMILES CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].O.[Na+]
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Thermo Scientific Chemicals
455300010 		1 g
707.79 NOK
1g
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Thermo Scientific Chemicals
455300050 		5 g N/A N/A N/A
Description

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Cloxacillin sodium salt monohydrate is a chlorinated derivative of oxacillin that shows β-lactamase-resistant antibiotic activity

• This compound inhibits the last stage of bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), which results in cell lysis, that is mediated by bacterial cell wall autolytic enzymes

Applications

• Cloxacillin sodium salt monohydrate targets gram-positive bacteria, and is effective against staphylococci that produce β-lactamase

• It acts in vitro against both penicillin gram-resistant and gram-sensitive staphylococci, certain streptococci, and pneumococci

• This compound is commonly used in vivo and in vitro studies as AmpC β-lactamase inhibitor in combination with β-lactam antibiotics

Specifications

Chemical Identifiers

7081-44-9
475.876
23675743
sodium;(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrate
C19H19ClN3NaO6S
KCUWTKOTPIUBRI-VICXVTCVSA-M
CHEBI:34978
CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].O.[Na+]

Specifications

Cloxacillin Sodium Salt Monohydrate
Authentic
C19H19ClN3NaO6S
CC1=C(C(=NO1)C2=CC=CC=C2Cl)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].O.[Na+]
475.876
CHEBI:34978
≥94% (HPLC)
7081-44-9
3.0 to 5.0%
KCUWTKOTPIUBRI-VICXVTCVSA-M
sodium;(2S,5R,6R)-6-[[3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;hydrate
23675743
475.88
Cloxacillin sodium salt monohydrate
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Safety and Handling

Safety and Handling

GHS H Statement Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled.

GHS P Statement IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician if you feel unwell. Wear protective gloves/protective clothing/eye protection/face protection.

Danger

Product Identifier
  • Cloxacillin sodium salt monohydrate

Signal Word
  • Danger

Hazard Category
  • Serious eye damage/eye irritation Category 2
  • Respiratory sensitiser Category 1
  • Skin corrosion/irritation Category 2
  • Skin sensitiser Category 1
  • Specific target organ toxicity Category 3

Hazard Statement
  • H317-May cause an allergic skin reaction.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H319-Causes serious eye irritation.
  • H335-May cause respiratory irritation.
  • H315-Causes skin irritation.

Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.

SDS
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Product Certifications

RUO – Research Use Only

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