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CD134 Rat anti-Mouse, CoraLite 488, Clone: OX-86, Proteintech

Rat Monoclonal Antibody

Brand:  Proteintech CL488-65136-100TESTS

Product Code. 17214696

  • 1181.58 NOK / 100 reactions

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Description

Description

CD134, also known as OX40 and TNFRSF4, is a member of the TNFR-superfamily of receptors (PMID: 2828930; 9766631). It is a type I transmembrane protein predominantly expressed on activated T cells which include CD4 and CD8 T cells, Th2, Th1, and Th17 cells, as well as regulatory T cells (Tregs) (PMID: 20307208). CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule (PMID: 26215166). CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmune diseases, cancer and infectious disease (PMID: 26215166; 19426222).

Specifications

Specifications

CD134
Monoclonal
5 μL/Test
Rat
Primary
Human, Mouse, Rat
IgG1 κ
Flow Cytometry
OX-86
CoraLite 488
100 Tests
22163
Liquid
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