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Thermo Scientific Chemicals Bilirubin, 98+%, Thermo Scientific Chemicals

Bilirubin 97%, CAS # 635-65-4, is a tetrapyrroliccompound found in bile that is a product of heme catabolism.

Chemical Identifiers

CAS 635-65-4
Molecular Formula C33H36N4O6
Molecular Weight (g/mol) 584.67
MDL Number MFCD00005499
InChI Key BPYKTIZUTYGOLE-IFADSCNNSA-N
Synonym bilirubin, hematoidin, hemetoidin, bilirubin ix-alpha, principal bile pigment, unii-rfm9x3lj49, bilirubin ixalpha, 21h-biline-8,12-dipropanoic acid, 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo, rfm9x3lj49, biline-8,12-dipropionic acid, 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl
PubChem CID 5280352
ChEBI CHEBI:16990
IUPAC Name 3-[2-[[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
SMILES CC1=C(C=C)\C(NC1=O)=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(CCC(O)=O)C(C)=C(N2)\C=C2/NC(=O)C(C=C)=C2C)N1
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Description

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Bilirubin is a degradation product of heme following the activity of heme oxidase. Bilirubin is produced in the reticuloendothelial system and conjugated in the liver. It appears as an orange-yellow pigment that is secreted in the bile
  • High levels of unconjugated bilirubin can result in jaundice, a condition of the yellowing of skin and eyes. This can be toxic and may be a sign of severe liver disease
  • Bilirubin has been seen to have functions including cell signaling, metabolism modulation, and immune regulation
  • It has protective antioxidant activity at moderate levels

Application

  • Bilirubin is widely used in studies of liver function and disease, such as hepatitis or cirrhosis
  • As an antioxidant, bilirubin has been studied in protection against H2O2-mediated cell death
  • It can be used as a scavenger of reactive oxygen species (ROS) or as an inhibitor of NADPH oxidase
Specifications

Chemical Identifiers

635-65-4
584.67
BPYKTIZUTYGOLE-IFADSCNNSA-N
5280352
3-[2-[[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
C33H36N4O6
MFCD00005499
bilirubin, hematoidin, hemetoidin, bilirubin ix-alpha, principal bile pigment, unii-rfm9x3lj49, bilirubin ixalpha, 21h-biline-8,12-dipropanoic acid, 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo, rfm9x3lj49, biline-8,12-dipropionic acid, 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl
CHEBI:16990
CC1=C(C=C)\C(NC1=O)=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(CCC(O)=O)C(C)=C(N2)\C=C2/NC(=O)C(C=C)=C2C)N1

Specifications

635-65-4
100.0
1.8% max. (60°C, 2 hrs) (vacuum)
98+%
MFCD00005499
bilirubin, hematoidin, hemetoidin, bilirubin ix-alpha, principal bile pigment, unii-rfm9x3lj49, bilirubin ixalpha, 21h-biline-8,12-dipropanoic acid, 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo, rfm9x3lj49, biline-8,12-dipropionic acid, 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl
CC1=C(C=C)\C(NC1=O)=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(CCC(O)=O)C(C)=C(N2)\C=C2/NC(=O)C(C=C)=C2C)N1
584.67
CHEBI:16990
98%
Bilirubin
98.5
Brown-Red to Orange
Authentic
C33H36N4O6
15, 1222
BPYKTIZUTYGOLE-IFADSCNNSA-N
3-[2-[[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
5280352
584.67
Fine Crystalline Powder
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